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Clinical and genetic characteristics of hemoglobin H disease in Iran.

Pediatric hematology and oncology - 1 Sept 2022

Abolghasemi Hassan, Kamfar Sharareh, Azarkeivan Azita, Karimi Mehran, Keikhaei Bijan, Abolghasemi Fahimeh, Radfar Mohammad H, Eshghi Peyman, Alavi Samin

Abstract excerpt

Hemoglobin H (Hb H) disease is a subtype of α-thalassemia caused by deletional and/or non-deletional mutations in three alpha-globin genes in which the various genotypes determine the disease severity. This study was aimed to investigate the frequency of alpha gene mutations and genotypes and their correlation with hematological and clinical characteristics in Iran. Among 202 patients diagnosed with Hb H disease...

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Identifiers

PMID: 34951342
DOI: 10.1080/08880018.2021.2017529

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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