Article
Molecular analysis of alpha- and beta-thalassemia in Meizhou region and comparison of gene mutation spectrum with different regions of southern China.
Journal of clinical laboratory analysis - 1 Dec 2021
Wu Heming, Huang Qingyan, Yu Zhikang, Zhong Zhixiong
Abstract excerpt
BACKGROUND: Thalassemia is a group of inherited autosomal recessive hemolytic anemia disease caused by reduced or absent synthesis of globin chain/chains of hemoglobin. Only few studies showed the molecular characterization of α- and β-thalassemia in Meizhou city of China. METHODS: A total of 22,401 individuals were collected; hematological and hemoglobin electrophoresis analysis and thalassemia genetic testing...
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