Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Bidirectional Mendelian Randomization Study of Personality Traits Reveals a Positive Feedback Loop Between Neuroticism and Back Pain

1 Jun 2023

Abstract excerpt

We conducted a bidirectional Mendelian randomization study to examine the causal effects of six personality traits (anxiety, neuroticism, extraversion, openness to experience, agreeableness, and conscientiousness) on back pain associated with health care use and the causal effect of back pain on the same risk factors. Genetic instruments for the personality traits and back pain were obtained from the largest...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Fibromyalgia and Chronic Fatigue Syndrome Research
Share to Musculoskeletal pain and rehabilitation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37270142
DOI: 10.1016/j.jpain.2023.05.012

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Bidirectional Mendelian Randomization Study of Personality Traits Reveals a Positive Feedback Loop Between Neuroticism and Back PainPMID 37270142Read ↗

Genetic correlations between pain phenotypes and depression and neuroticism.Semantic proximity Read ↗

Causality between neuroticism personality clusters and female reproductive diseases in European population: a two-sample bidirectional mendelian randomization studySemantic proximity Read ↗

Causal relationship between neuroticism and bone mineral density: A univariable and multivariable Mendelian randomization study.Semantic proximity Read ↗

Genetic relationships between chronic pain, psychopathologies, and neuroticismSemantic proximity Read ↗

Unraveling the brain-joint axis: genetic, transcriptomic, and cohort insights from neuroticism to osteoarthritis.Semantic proximity Read ↗

Insight into the genetic architecture of back pain and its risk factors from a study of 509,000 individualsSemantic proximity Read ↗

Meta-analysis of genome-wide SNP- and pathway-based associations for facets of neuroticism.Semantic proximity Read ↗

A Data-Driven Biopsychosocial Framework Determining the Spreading of Chronic PainSemantic proximity Read ↗

Five-factor personality traits and pain sensitivity: a twin study.Semantic proximity Read ↗

Causal influences of neuroticism on mental health and cardiovascular disease.Semantic proximity Read ↗

Exploring the bidirectional relationship between pain and mental disorders: a comprehensive Mendelian randomization study.Semantic proximity Read ↗

Neuroticism and inflammatory skin diseases: a bidirectional Mendelian randomization study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.