Article

Genetic relationships between chronic pain, psychopathologies, and neuroticism

2023-06-27

Abstract excerpt

Chronic pain and psychiatric conditions have consistently demonstrated substantial overlap in risk factors, epidemiology, and effective treatments. Previous work has identified cross-condition latent factors underlying shared genetic risk for several distinct psychiatric conditions and pain conditions. Here, we sought to examine the relationships between these latent genetic factors to determine biological mechani...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 2e38801c-4cbf-5b97-a3df-a48f36d03798
DOI: 10.1101/2023.06.20.23291689

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Genetic relationships between chronic pain, psychopathologies, and neuroticismDOI 10.1101/2023.06.20.23291689Read

Genetic correlations between pain phenotypes and depression and neuroticism.Semantic proximity Read

Genetic and epigenetic epidemiology of chronic widespread painSemantic proximity Read

Genome-wide by trait interaction analyses with neuroticism reveal chronic pain-associated depression as a distinct genetic subtypeSemantic proximity Read

Genetic risk shared across 24 chronic pain conditions: identification and characterization with genomic structural equation modelingSemantic proximity Read

A Shared Genetic Signature for Common Chronic Pain Conditions and its Impact on Biopsychosocial Traits.Semantic proximity Read

A Data-Driven Biopsychosocial Framework Determining the Spreading of Chronic PainSemantic proximity Read

A shared genetic signature for common chronic pain conditions and its impact on biopsychosocial traitsSemantic proximity Read

Analysis of genetically independent phenotypes identifies shared genetic factors associated with chronic musculoskeletal pain conditions.Semantic proximity Read

Investigating the shared genetic architecture and causal relationship between pain and neuropsychiatric disordersSemantic proximity Read

Genome wide association joint analysis reveals 99 risk loci for pain susceptibility and pleiotropic relationships with psychiatric, metabolic, and immunological traits.Semantic proximity Read

Understanding the comorbidities among psychiatric disorders, chronic low-back pain, and spinal degenerative disease using observational and genetically informed analysesSemantic proximity Read

Genetic and Environmental Risk for Chronic Pain and the Contribution of Risk Variants for Major Depressive Disorder: A Family-Based Mixed-Model AnalysisSemantic proximity Read