Article
BRAF Mutations in CNS Tumors-Prognostic Markers and Therapeutic Targets.
CNS drugs - 1 Jul 2023
Muniz Thiago P, Mason Warren P
Abstract excerpt
Gliomas are a heterogeneous group of brain tumors with limited therapeutic options. However, identification of BRAF V600E mutations in a subset of gliomas has provided a genomic-targeted approach for management of these diseases. In this review, we aimed to review the role of BRAF V600E in gliomagenesis, to characterize concurrent genomic alterations and their potential prognostic implications, and to review...
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