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Article

Targeted Therapy for BRAF Mutant Brain Tumors.

Current treatment options in oncology - 6 Oct 2021

Rayi Appaji, Alnahhas Iyad, Ong Shirley, Giglio Pierre, Puduvalli Vinay K

Abstract excerpt

OPINION STATEMENT: Molecular heterogeneity has confounded attempts to target individual pathways in brain tumors. However, gliomas with BRAF mutations have been identified as being uniquely vulnerable to targeted therapies. Such mutations are predominantly seen in brain tumors of the adolescent and young adult population. Given that accurate and timely identification of such mutations is essential for offering...

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PMID: 34613491
DOI: 10.1007/s11864-021-00901-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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