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Molecular biology of high-grade gliomas: what should the clinician know?

10 Dec 2013

Abstract excerpt

The current World Health Organization classification system of primary brain tumors is solely based on morphologic criteria. However, there is accumulating evidence that tumors with similar histology have distinct molecular signatures that significantly impact treatment response and survival. Recent practice-changing clinical trials have defined a role for routine assessment of O-6-methylguanine-DNA...

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PMID: 24325789
DOI: 10.5732/cjc.013.10218

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