Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The implications of physiological biomolecular condensates in amyotrophic lateral sclerosis.

Seminars in cell & developmental biology - 15 Mar 2024

Fakim Hana, Vande Velde Christine

Abstract excerpt

In recent years, there has been an emphasis on the role of phase-separated biomolecular condensates, especially stress granules, in neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS). This is largely due to several ALS-associated mutations occurring in genes involved in stress granule assembly and observations that pathological inclusions detected in ALS patient neurons contain stress granule...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amyotrophic Lateral Sclerosis
Share to Amyotrophic Lateral Sclerosis Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA-Binding Proteins

Share to Mutation

Share to Neurodegenerative Diseases

Share to Neurogenetic and Muscular Disorders Research

Share to RNA Research and Splicing

Source

Identifiers

PMID: 37268555
DOI: 10.1016/j.semcdb.2023.05.006

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The implications of physiological biomolecular condensates in amyotrophic lateral sclerosis.PMID 37268555Read ↗

Stress Granule Homeostasis, Aberrant Phase Transition, and Amyotrophic Lateral Sclerosis.Semantic proximity Read ↗

Regulation of physiological and pathological condensates by molecular chaperonesSemantic proximity Read ↗

Pathological phase transitions in ALS-FTD impair dynamic RNA-protein granules.Semantic proximity Read ↗

Stress granules as crucibles of ALS pathogenesisSemantic proximity Read ↗

Aberrant Stress Granule Dynamics and Aggrephagy in ALS PathogenesisSemantic proximity Read ↗

Alterations in stress granule dynamics driven by TDP-43 and FUS: a link to pathological inclusions in ALS?Semantic proximity Read ↗

Stress granule mediated protein aggregation and underlying gene defects in the FTD-ALS spectrumSemantic proximity Read ↗

Stress Granule Dysregulation in Amyotrophic Lateral SclerosisSemantic proximity Read ↗

Loss of PML nuclear bodies in familial amyotrophic lateral sclerosis-frontotemporal dementiaSemantic proximity Read ↗

TDP-43 and NEAT long non-coding RNA: Roles in neurodegenerative diseaseSemantic proximity Read ↗

Stress granules regulate stress-induced paraspeckle assemblySemantic proximity Read ↗

Linking hnRNP Function to ALS and FTD PathologySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.