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Article

Fusion of bone marrow-derived cells with cancer cells: metastasis as a secondary disease in cancer

3 Mar 2014

Abstract excerpt

This perspective article highlights the leukocyte-cancer cell hybrid theory as a mechanism for cancer metastasis. Beginning from the first proposal of the theory more than a century ago and continuing today with the first proof for this theory in a human cancer, the hybrid theory offers a unifying explanation for metastasis. In this scenario, leukocyte fusion with a cancer cell is a secondary disease superimposed...

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PMID: 24589183
DOI: 10.5732/cjc.013.10243

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