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Multi-omic features of oesophageal adenocarcinoma in patients treated with preoperative neoadjuvant therapy

31 May 2023

Abstract excerpt

Oesophageal adenocarcinoma is a poor prognosis cancer and the molecular features underpinning response to treatment remain unclear. We investigate whole genome, transcriptomic and methylation data from 115 oesophageal adenocarcinoma patients mostly from the DOCTOR phase II clinical trial (Australian New Zealand Clinical Trials Registry-ACTRN12609000665235), with exploratory analysis pre-specified in the study...

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PMID: 37258531
DOI: 10.1038/s41467-023-38891-x

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