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Spatial transcriptomics of murine bone marrow megakaryocytes at single-cell resolution

20 Apr 2023

Abstract excerpt

Background While megakaryocytes are known for making platelets, recent single-cell RNA sequencing data have revealed subpopulations of megakaryocytes with predicted immunoregulatory and bone marrow niche-supporting roles. Although these studies uncovered interesting information regarding the transcriptional variation of megakaryocytes, the generation, localization, and regulation of these subsets have not yet...

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PMID: 37255850
DOI: 10.1016/j.rpth.2023.100158

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