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Article

SERPINE1 mRNA Binding Protein 1 Is Associated with Ischemic Stroke Risk: A Comprehensive Molecular-Genetic and Bioinformatics Analysis of SERBP1 SNPs.

International journal of molecular sciences - 13 May 2023

Shilenok Irina, Kobzeva Ksenia, Stetskaya Tatiana, Freidin Maxim, Soldatova Maria, Deykin Alexey, Soldatov Vladislav, Churnosov Mikhail, Polonikov Alexey, Bushueva Olga

Abstract excerpt

The SERBP1 gene is a well-known regulator of SERPINE1 mRNA stability and progesterone signaling. However, the chaperone-like properties of SERBP1 have recently been discovered. The present pilot study investigated whether SERBP1 SNPs are associated with the risk and clinical manifestations of ischemic stroke (IS). DNA samples from 2060 unrelated Russian subjects (869 IS patients and 1191 healthy controls) were...

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Identifiers

PMID: 37240062
DOI: 10.3390/ijms24108716
PMCID: PMC10217814

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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