Association of SUMOylation Pathway Genes With Stroke in a Genome-Wide Association Study in India.

doi:10.1212/WNL.0000000000012258

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Association of SUMOylation Pathway Genes With Stroke in a Genome-Wide Association Study in India.

Neurology - 27 Jul 2021

Kumar Amit, Chauhan Ganesh, Sharma Shriram, Dabla Surekha, Sylaja P N, Chaudhary Neera, Gupta Salil, Agrawal Chandra Sekhar, Anand Kuljeet Singh, Srivastava Achal Kumar, Vibha Deepti, Sagar Ram, Raj Ritesh, Maheshwari Ankita, Vivekanandhan Subbiah, Kaul Bhavna, Raghavan Samudrala, Gorthi Sankar Prasad, Mohania Dheeraj, Kaushik Samander, Yadav Rohtas Kanwar, Hazarika Anjali, Sharma Pankaj, Prasad Kameshwar

Abstract excerpt

OBJECTIVE: To undertake a genome-wide association study (GWAS) to identify genetic variants for stroke in an Indian population. METHODS: In a hospital-based case-control study, 8 teaching hospitals in India recruited 4,088 participants, including 1,609 stroke cases. Imputed genetic variants were tested for association with stroke subtypes using both single-marker and gene-based tests. Association with vascular...

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PMID: 34031191
DOI: 10.1212/WNL.0000000000012258
PMCID: PMC8362360

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