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Article

A functional polymorphism of PON1 interferes with microRNA binding to increase the risk of ischemic stroke and carotid atherosclerosis.

Atherosclerosis - 1 May 2013

Liu Mu-En, Liao Yi-Chu, Lin Ruey-Tay, Wang Yung-Song, Hsi Edward, Lin Hsiu-Fen, Chen Ku-Chung, Juo Suh-Hang H

Abstract excerpt

OBJECTIVE: Single nucleotide polymorphisms (SNPs) located at microRNA (miRNA) binding sites (miR-SNPs) can affect the expression of genes. This study aimed to identify the miR-SNPs associated with atherosclerosis and stroke. METHODS: Patients with ischemic stroke (n = 657) and stroke- and myocardial infarction-free volunteers (n = 1571) were enrolled. The carotid intima-media thickness (IMT) was measured in the...

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Identifiers

PMID: 23497787
DOI: 10.1016/j.atherosclerosis.2013.01.036

Genes

PON1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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