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Article

Whole-Exome Sequencing Analyses Support a Role of Vitamin D Metabolism in Ischemic Stroke.

Stroke - 1 Mar 2023

Xie Yuhan, Acosta Julián N, Ye Yixuan, Demarais Zachariah S, Conlon Carolyn J, Chen Ming, Zhao Hongyu, Falcone Guido J

Abstract excerpt

BACKGROUND: Ischemic stroke (IS) is a highly heritable trait, and genome-wide association studies have identified several commonly occurring susceptibility risk loci for this condition. However, there are limited data on the contribution of rare genetic variation to IS. METHODS: We conducted an exome-wide study using whole-exome sequencing data from 152 058 UK Biobank participants, including 1777 IS cases. We...

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Identifiers

PMID: 36762557
DOI: 10.1161/STROKEAHA.122.040883
PMCID: PMC10467223

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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