Article
Evolutionary trade-off and mutational bias could favor transcriptional over translational divergence within paralog pairs.
PLoS genetics - 1 May 2023
Aubé Simon, Nielly-Thibault Lou, Landry Christian R
Abstract excerpt
How changes in the different steps of protein synthesis-transcription, translation and degradation-contribute to differences of protein abundance among genes is not fully understood. There is however accumulating evidence that transcriptional divergence might have a prominent role. Here, we show that yeast paralogous genes are more divergent in transcription than in translation. We explore two causal mechanisms...
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