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The PD-1 single-nucleotide polymorphism rs11568821 and rs2227981 as a novel prognosis model in a triple-negative breast cancer patient.

Molecular biology reports - 1 Jul 2023

Boguszewska-Byczkiewicz Katarzyna, Wow Thomas, Szymańska Bożena, Kosny Michał, Kolacinska-Wow Agnieszka

Abstract excerpt

INTRODUCTION: The aim of the study is to determine the relationship between polymorphisms rs11568821 C/T and at rs2227981 G/A in the programmed cell death 1 gene (PDCD1) and the clinicopathologic characteristics of triple negative breast cancer patient (TNBC). MATERIAL AND METHODS: The study included 30 TNBC patients and 30 healthy controls. Genotyping was performed with allelic discrimination using PCR with...

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PMID: 37212960
DOI: 10.1007/s11033-023-08423-3

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