Article

The molecular portrait of triple-negative breast cancer: the LAG3 gene single nucleotide polymorphism rs2365094 has no impact on the clinical picture

2022-12-22

Abstract excerpt

<h4>Introduction: </h4> Triple-negative breast cancer (TNBC) is characterized by a lack of estrogen, progesterone and human epidermal growth factor receptors. It is the one of most heterogeneous and highly-aggressive breast cancers, resulting in fast progression. In humans, the LAG3 gene is located on chromosome 12p13 and encodes an immune-regulatory molecule. LAG3 gene polymorphisms may influence the clinicopatho...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 3ed0985e-9900-5e2a-98b1-d3dce65eef89
DOI: 10.21203/rs.3.rs-2389420/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The molecular portrait of triple-negative breast cancer: the LAG3 gene single nucleotide polymorphism rs2365094 has no impact on the clinical pictureDOI 10.21203/rs.3.rs-2389420/v1Read

Molecular and Clinical Characterization of LAG3 in Breast Cancer Through 2994 SamplesSemantic proximity Read

The Investigation of Associations between TP53 rs1042522, BBC3 rs2032809, CCND1 rs9344, EGFR rs2227983 Polymorphisms and Breast Cancer Phenotype and PrognosisSemantic proximity Read

PD-L1 Gene Polymorphisms rs822336 G>C and rs822337 T>A: Promising Prognostic Markers in Triple Negative Breast Cancer PatientsSemantic proximity Read

Elevated sHLA-G plasma levels post chemotherapy combined with ILT-2 rs10416697C allele status of the sHLA-G-related receptor predict poorest disease outcome in early triple-negative breast cancer patients.Semantic proximity Read

Early triple negative breast cancers in a Singapore cohort exhibit high PIK3CA mutation rates associated with low PD-L1 expressionSemantic proximity Read

A Prospective Evaluation of the Association between a Single Nucleotide Polymorphism rs3775291 in Toll-Like Receptor 3 and Breast Cancer Relapse.Semantic proximity Read

Prognostic Impact of LAG-3 Expression in Early Breast CancerSemantic proximity Read

Association analyses of a genetic variant in long non-coding RNA MEG3 with breast cancer susceptibility and serum MEG3 expression level in the Egyptian population.Semantic proximity Read

The breast surgeon in the molecular era: the PD-1 single‐nucleotide polymorphism rs11568821 and rs2227981 as a novel prognosis model in a triple-negative breast cancer patientSemantic proximity Read

CHST9 rs1436904 genetic variant contributes to prognosis of triple-negative breast cancer.Semantic proximity Read

A single-nucleotide polymorphism in the 3'-UTR region of the adipocyte fatty acid binding protein 4 gene is associated with prognosis of triple-negative breast cancer.Semantic proximity Read

The risk allele of SNP rs3803662 and the mRNA level of its closest genes TOX3 and LOC643714 predict adverse outcome for breast cancer patients.Semantic proximity Read