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Novel Association of IGF2BP2 Gene Variants With Altered Risk of Breast Cancer and as Potential Molecular Biomarker of Triple Negative Breast Cancer.

Clinical breast cancer - 1 Apr 2023

Almawi Wassim Y, Zidi Sabrina, Sghaier Ikram, El-Ghali Rabeb M, Daldoul Amira, Midlenko Anna

Abstract excerpt

BACKGROUND: Several studies documented that insulin-like growth factor-2 mRNA-binding protein 2 (IGF2BP2) contributes to carcinogenesis, and 1 report documented the association of IGF2BP2 rs4402960 with increased risk of breast cancer (BC). This study investigated the association of rs4402960 and rs1470579 IGF2BP2 variants with BC and triple negative BC (TNBC). MATERIALS AND METHODS: This case-control study...

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PMID: 36653207
DOI: 10.1016/j.clbc.2022.12.017

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