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Article

Programmed death-ligand 1 single nucleotide polymorphism affects breast cancer chemosensitivity and adverse events in the neoadjuvant setting.

The International journal of biological markers - 1 Sept 2020

Lu Jinglu, Wu Ziping, Peng Jing, Xu Shuguang, Zhou Liheng, Lin Yanping, Wang Yan, Yin Wenjin, Lu Jinsong

Abstract excerpt

OBJECTIVE: We aimed to determine whether single nucleotide polymorphisms in the PD-L1 gene are related to the response and adverse events of patients receiving neoadjuvant therapy and to explore the mechanism. METHODS: Nine single nucleotide polymorphisms of PD-L1 were selected and tested among patients before neoadjuvant therapy. Four models were used in single nucleotide polymorphism genotype analysis: the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33073683
DOI: 10.1177/1724600820926172

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