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PD-L1 Gene Polymorphisms rs822336 G>C and rs822337 T>A: Promising Prognostic Markers in Triple Negative Breast Cancer Patients

Medicina (Kaunas, Lithuania) - 6 Oct 2022

Makrantonakis Andreas-Evangelos, Zografos Eleni, Gazouli Maria, Dimitrakakis Konstantinos, Toutouzas Konstantinos G, Zografos Constantinos G, Kalapanida Despoina, Tsiakou Andriani, Samelis George, Zagouri Flora

Abstract excerpt

Background and Objectives: Triple-negative breast cancer (TNBC) is a highly heterogeneous subtype that is associated with unresponsiveness to therapy and hence with high mortality rates. In this study we aimed to investigate the prognostic role of the rs822336 G>C and rs822337 T>A polymorphisms of the PD-L1 (Programmed Death-Ligand 1) in TNBC patients. Materials and methods: Formalin-fixed paraffin-embedded...

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Identifiers

PMID: 36295559
DOI: 10.3390/medicina58101399
PMCID: PMC9612177

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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