Article
High-Quality Sleep Mitigates ABCA7-Related Generalization Deficits in Healthy Older African Americans.
Journal of Alzheimer's disease : JAD - 1 Jan 2023
Sinha Neha, Fausto Bernadette A, Mander Bryce, Gluck Mark A
Abstract excerpt
BACKGROUND: Both sleep deficiencies and Alzheimer's disease (AD) disproportionately affect older African Americans. Genetic susceptibility to AD further compounds risk for cognitive decline in this population. Aside from APOE ɛ4, ABCA7 rs115550680 is the strongest genetic locus associated with late-onset AD in African Americans. While sleep and ABCA7 rs115550680 independently influence late-life cognitive...
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