Article

Preserved Medial Temporal Lobe Flexibility Predicts Memory Generalization Only in the Context of Good Sleep Quality among Older African Americans

2026-06-17

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Objectives</h4> Poor sleep quality is a risk factor for Alzheimer’s disease (AD). Older African Americans experience disproportionately high rates of sleep disturbance and AD. Medial temporal lobe (MTL) flexibility reflects dynamic neural reorganization and may be a marker of generalization performance. This study examined whether sleep quality moderates the association between MTL flexibil...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: b9ef4bb7-c3a8-524d-87f7-ef43fa7d09ba
DOI: 10.64898/2026.06.15.26355704

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Preserved Medial Temporal Lobe Flexibility Predicts Memory Generalization Only in the Context of Good Sleep Quality among Older African AmericansDOI 10.64898/2026.06.15.26355704Read

High-Quality Sleep Mitigates ABCA7-Related Generalization Deficits in Healthy Older African Americans.Semantic proximity Read

ABCA7 rs115550680 risk allele carriers have lower medial temporal lobe dynamic network flexibility than APOE-ε4 allele carriers among older African Americans.Semantic proximity Read

Older adults at greater risk for Alzheimer’s disease show stronger associations between sleep apnea severity and verbal memorySemantic proximity Read

HK-ASAP study: protocol for a prospective cohort study on sleep quality, brain reserve and cognitive phenotypes in community-dwelling older adults.Semantic proximity Read

Self-Reported Sleep Relates to Microstructural Hippocampal Decline in β-Amyloid Positive Adults Beyond Genetic RiskSemantic proximity Read

Cognitive reserve and gamma entrainment-related network changes in prodromal Alzheimer’s diseaseSemantic proximity Read

The structure of hippocampal circuitry relates to rapid category learning in humansSemantic proximity Read

Dynamic functional connectivity in modular organization of the hippocampal network marks memory phenotypes in temporal lobe epilepsy.Semantic proximity Read

Potential cognitive and neural benefits of a computerised cognitive training programme based on Structure Learning in healthy adults: Study protocol for a randomised controlled trial.Semantic proximity Read

Network efficiency predicts resilience to cognitive decline in elderly at risk for Alzheimer’sSemantic proximity Read

Concurrent synaptic and systems memory consolidation during sleep.Semantic proximity Read

Sleep leads to system-wide neural changes independent of allo- and egocentric spatial training in humans and ratsSemantic proximity Read