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Article

Global status of phenotypic pyrazinamide resistance in Mycobacterium tuberculosis clinical isolates: an updated systematic review and meta-analysis.

Journal of chemotherapy (Florence, Italy) - 1 Nov 2023

Wang Zheming, Tang Zhihua, Heidari Hamid, Molaeipour Leila, Ghanavati Roya, Kazemian Hossein, Koohsar Faramarz, Kouhsari Ebrahim

Abstract excerpt

Pyrazinamide (PZA) is an essential first-line tuberculosis drug for its unique mechanism of action active against multidrug-resistant-TB (MDR-TB). Thus, the aim of updated meta-analysis was to estimate the PZA weighted pooled resistance (WPR) rate in M. tuberculosis isolates based on publication date and WHO regions. We systematically searched the related reports in PubMed, Scopus, and Embase (from January 2015...

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Identifiers

PMID: 37211822
DOI: 10.1080/1120009X.2023.2214473

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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