Article
Preimplantation genetic testing for mitochondrial DNA mutation: ovarian response to stimulation, outcomes and follow-up.
Reproductive biomedicine online - 1 Jul 2023
Mayeur Anne, Benaloun Emmanuelle, Benguigui Jonas, Duperier Constance, Hesters Laetitia, Chatzovoulou Kalliopi, Monnot Sophie, Grynberg Michael, Steffann Julie, Frydman Nelly, Sonigo Charlotte
Abstract excerpt
RESEARCH QUESTION: How do carriers of pathogenic mitochondrial DNA (mtDNA) respond to ovarian stimulation? DESIGN: A single-centre, retrospective study conducted between January 2006 and July 2021 in France. Ovarian reserve markers and ovarian stimulation cycle outcomes were compared for couples undergoing preimplantation genetic testing (PGT) for maternally inherited mtDNA disease (n = 18) (mtDNA-PGT group) with...
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