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Article

Preimplantation genetic diagnosis for a carrier with m.3697G > A mitochondrial DNA mutation.

Journal of assisted reproduction and genetics - 1 Dec 2021

Ji Dongmei, Li Xinyuan, Pan Jianxin, Zong Kai, Chen Dawei, Marley Jordan Lee, Zou Weiwei, Deng Xiaohong, Cao Yu, Zhang Zhiguo, Zhou Ping, Sha Hongying, Cao Yunxia

Abstract excerpt

OBJECTIVE: To explore inheritance of the m.3697G > A mitochondrial DNA (mtDNA) mutation and the effectiveness of preimplantation genetic diagnosis (PGD) for the carrier. METHODS: The study encompassed a pedigree of m.3697G > A mtDNA mutation, including one asymptomatic patient who pursued for PGD treatment. Twelve cumulus oocyte complexes (COCs) were collected in the first PGD cycle and 11 COCs in the second...

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Identifiers

PMID: 34802141
DOI: 10.1007/s10815-021-02354-3
PMCID: PMC8666394

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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