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Article

Novel reproductive technologies to prevent mitochondrial disease.

Human reproduction update - 1 Sept 2017

Craven Lyndsey, Tang Mao-Xing, Gorman Gráinne S, De Sutter Petra, Heindryckx Björn

Abstract excerpt

BACKGROUND: The use of nuclear transfer (NT) has been proposed as a novel reproductive treatment to overcome the transmission of maternally-inherited mitochondrial DNA (mtDNA) mutations. Pathogenic mutations in mtDNA can cause a wide-spectrum of life-limiting disorders, collectively known as mtDNA disease, for which there are currently few effective treatments and no known cures. The many unique features of mtDNA...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 28651360
DOI: 10.1093/humupd/dmx018

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PGD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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