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Article

Dealing with uncertainties: ethics of prenatal diagnosis and preimplantation genetic diagnosis to prevent mitochondrial disorders

3 Dec 2007

Abstract excerpt

This paper aims to address the ethical issues regarding prenatal diagnosis and preimplantation genetic diagnosis (PGD) of mitochondrial disorders. Owing to the absence of effective treatment, the prevention of the transmission of mitochondrial disorders is considered to be of key importance. The characteristics of mtDNA, such as heteroplasmy and the genetic bottleneck, make it difficult to estimate recurrence...

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Share to Ethics and Legal Issues in Pediatric Healthcare
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 18056133
DOI: 10.1093/humupd/dmm037

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