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Article

ANGPTL4 is a potential driver of HCV-induced peripheral insulin resistance.

Scientific reports - 25 Apr 2023

Gomes Diana, Sobolewski Cyril, Conzelmann Stéphanie, Schaer Tifany, Lefai Etienne, Alfaiate Dulce, Tseligka Eirini D, Goossens Nicolas, Tapparel Caroline, Negro Francesco, Foti Michelangelo, Clément Sophie

Abstract excerpt

Chronic hepatitis C (CHC) is associated with the development of metabolic disorders, including both hepatic and extra-hepatic insulin resistance (IR). Here, we aimed at identifying liver-derived factor(s) potentially inducing peripheral IR and uncovering the mechanisms whereby HCV can regulate the action of these factors. We found ANGPTL4 (Angiopoietin Like 4) mRNA expression levels to positively correlate with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37185283
DOI: 10.1038/s41598-023-33728-5
PMCID: PMC10130097

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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