Article
Chronic hepatitis c genotype-4 infection: role of insulin resistance in hepatocellular carcinoma.
Virology journal - 1 Nov 2011
Mohamed Amal A, Loutfy Samah A, Craik James D, Hashem Abdel Gawad M, Siam Ibrahem
Abstract excerpt
BACKGROUND: Hepatitis C virus (HCV) is a major cause of chronic hepatitis and hepatocellular carcinoma (HCC) and different HCV genotypes show characteristic variations in their pathological properties. Insulin resistance (IR) occurs early in HCV infection and may synergize with viral hepatitis in HCC development. Egypt has the highest reported rates of HCV infection (predominantly genotype 4) in the world; this...
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