Article
Co-Mutations and Possible Variation Tendency of the Spike RBD and Membrane Protein in SARS-CoV-2 by Machine Learning.
International journal of molecular sciences - 25 Apr 2024
Ye Qiushi, Wang He, Xu Fanding, Zhang Sijia, Zhang Shengli, Yang Zhiwei, Zhang Lei
Abstract excerpt
Since the onset of the coronavirus disease 2019 (COVID-19) pandemic, SARS-CoV-2 variants capable of breakthrough infections have attracted global attention. These variants have significant mutations in the receptor-binding domain (RBD) of the spike protein and the membrane (M) protein, which may imply an enhanced ability to evade immune responses. In this study, an examination of co-mutations within the spike RBD...
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