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Article

Effect of the Fetal THRB Genotype on the Placenta.

The Journal of clinical endocrinology and metabolism - 18 Sept 2023

Salas-Lucia Federico, Stan Marius N, James Haleigh, Rajwani Aadil, Liao Xiao-Hui, Dumitrescu Alexandra M, Refetoff Samuel

Abstract excerpt

CONTEXT: Pregnant women with mutations in the thyroid hormone receptor beta (THRB) gene expose their fetuses to high thyroid hormone (TH) levels shown to be detrimental to a normal fetus (NlFe) but not to an affected fetus (AfFe). However, no information is available about differences in placental TH regulators. OBJECTIVE: To investigate whether there are differences in placentas associated with a NlFe compared...

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Source

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Identifiers

PMID: 37149816
DOI: 10.1210/clinem/dgad243
PMCID: PMC10505537

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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