Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

ABCB1 and ABCG2 expression in the placenta and fetus: an interspecies comparison

26 Aug 2010

Abstract excerpt

IMPORTANCE OF THE FIELD: ABCB1 and ABCG2 are efflux transporters which have a major impact on the pharmacological behavior of numerous drugs. They are expressed, for example, in the intestine, liver, kidney, BBB and placenta. It has become evident that ABCB1 and ABCG2 modify the pharmaco/toxicokinetics in the placenta and fetus and may consequently affect the outcome of pregnancy. AREAS COVERED IN THIS REVIEW:...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cholesterol and Lipid Metabolism
Share to Drug Transport and Resistance Mechanisms
Share to Pharmacogenetics and Drug Metabolism

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 20738225
DOI: 10.1517/17425255.2010.514264

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 10 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

ABCB1 and ABCG2 expression in the placenta and fetus: an interspecies comparisonPMID 20738225Read ↗

An update on expression and function of P-gp/ABCB1 and BCRP/ABCG2 in the placenta and fetusSemantic proximity Read ↗

BCRP/ABCG2 in the Placenta: Expression, Function and RegulationSemantic proximity Read ↗

Fetoprotective activity of breast cancer resistance protein (BCRP, ABCG2): expression and function throughout pregnancySemantic proximity Read ↗

ATP-Binding Cassette Efflux Transporters in Human PlacentaSemantic proximity Read ↗

Changes in Expression and Function of Placental and Intestinal P-gp and BCRP Transporters during PregnancySemantic proximity Read ↗

Regulation of drug transporter expression and function in the placentaSemantic proximity Read ↗

Placental transporter localization and expression in the Human: the importance of species, sex, and gestational age differences†Semantic proximity Read ↗

P-glycoprotein in the placenta: expression, localization, regulation and function.Semantic proximity Read ↗

Overview of Drug Transporters in Human PlacentaSemantic proximity Read ↗

ATP-binding cassette transporters in reproduction: a new frontierSemantic proximity Read ↗

Developmental expression of drug metabolizing enzymes and transporter proteins in human placenta and fetal tissuesSemantic proximity Read ↗

Drug Transporters Expressed in the Human Placenta and Models for Studying Maternal‐Fetal Drug TransferSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.