Article

Hypothyroidism in Pregnancy: Consequences to Neonatal Health

2001-06-01

Abstract excerpt

Pregnancy influences thyroid function in multiple ways. Not only does the maternal hypothalamic-pituitary-thyroid (HPT) axis undergo a series of adjustments, the fetus develops its own HPT axis and the placenta plays an active role in iodide and T4 transport and metabolism. Thus, an integrated three-compartment thyroid model exists during gestation (1). Early in pregnancy estrogen promotes production of a more hig...

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Thyroid Disorders and Treatments

Identifiers and source

Literature Corpus work: 27223523-76a4-518c-b519-e3c02cf8db7a
DOI: 10.1210/jc.86.6.2349

Open publication

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