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Multiple Mutations of CYP2C19, PON1 and ABCB1 Influence Platelet Response, Bleeding and Thrombosis Risk to Clopidogrel after Percutaneous Coronary Intervention: A Retrospective Study

2021-06-16

Abstract excerpt

<h4>Background: </h4> Different combinations of multiple mutations of CYP2C19, PON1and ABCB1 for the efficiency and safety of Clopidogrel in patients undergoing percutaneous coronary intervention (PCI) remain unclear. <h4>Methods: </h4>: 263 Chinese Han patients receiving 75mg Clopidogrel and 100mg Aspirin every day for 12 months after PCI were enrolled in this study. ADP-induced platelet aggregation rates, thromb...

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Literature Corpus work
cc4e5948-6ad8-51b9-aadd-85c87864219a
DOI
10.21203/rs.3.rs-582961/v1
Open publication

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Multiple Mutations of CYP2C19, PON1 and ABCB1 Influence Platelet Response, Bleeding and Thrombosis Risk to Clopidogrel after Percutaneous Coronary Intervention: A Retrospective StudyDOI 10.21203/rs.3.rs-582961/v1
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