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Detection of multiple druggable mutations of lung cancer from cytology specimens by MINtS: An advanced medicine A trial.

Cancer science - 1 Aug 2023

Fujita Kazutaka, Arai Ryo, Shoji Satoshi, Saito Ryota, Nomura Motoko, Hotta Takamasa, Asahina Hajime, Kawakami Masanori, Nakachi Ichiro, Hasegawa Yukihiro, Okafuji Kohei, Suzuki Aya, Miyanaga Akihiko, Sunaga Noriaki, Nagashima Hiromi, Ikeda Naoya, Watanabe Satoshi, Nagai Yoshiaki, Furuta Megumi, Kage Hidenori, Arai Daisuke, Fukuhara Tatsuro, Nakayama Masayuki, Morita Satoshi, Kobayashi Kunihiko, Hagiwara Koichi

Abstract excerpt

Most multigene mutation tests require tissue specimens. However, cytological specimens are easily obtained in the clinical practice and provide high-quality DNA and RNA. We aimed to establish a test that utilizes cytological specimens and performed a multi-institutional study to investigate the performance of MINtS, a test based on next-generation sequencing. A standard procedure for specimen isolation was...

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PMID: 37139543
DOI: 10.1111/cas.15831
PMCID: PMC10394136

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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