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Article

Molecular typing of lung adenocarcinoma on cytological samples using a multigene next generation sequencing panel.

PloS one - 1 Jan 2013

Scarpa Aldo, Sikora Katarzyna, Fassan Matteo, Rachiglio Anna Maria, Cappellesso Rocco, Antonello Davide, Amato Eliana, Mafficini Andrea, Lambiase Matilde, Esposito Claudia, Bria Emilio, Simonato Francesca, Scardoni Maria, Turri Giona, Chilosi Marco, Tortora Giampaolo, Fassina Ambrogio, Normanno Nicola

Abstract excerpt

Identification of driver mutations in lung adenocarcinoma has led to development of targeted agents that are already approved for clinical use or are in clinical trials. Therefore, the number of biomarkers that will be needed to assess is expected to rapidly increase. This calls for the implementation of methods probing the mutational status of multiple genes for inoperable cases, for which limited cytological or...

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Identifiers

PMID: 24236184
DOI: 10.1371/journal.pone.0080478
PMCID: PMC3827450

Genes

EGFR
KRAS
BRAF
FGFR3
MET
PTEN
SMAD4
STK11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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