Article
Sputum cell-free DNA for detection of alterations of multiple driver genes in lung adenocarcinoma.
Cancer cytopathology - 1 Feb 2023
Wang Zheng, Li Lin, Wang Yifei, Li Xiaoguang, Xu Yan, Wang Mengzhao, Liang Li, Wu Xiaonan, Tang Min, Li Yuanming, He Shurong, Du Jun, He Lei, Sun Mingjun, Yang Li, Di Jing, Gai Fei, Liu Dongge
Abstract excerpt
BACKGROUND: Sputum cell-free DNA (cfDNA) has been confirmed to be a valued surrogate sample for detection of EGFR mutations in patients with lung adenocarcinoma (LAC). Whether it is suitable for detection of mutations of multiple driver genes has not been reported. METHODS: A total of 83 patients with LAC were enrolled and their sputum and paired tumor samples were collected. A next-generation sequencing...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.