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Article

Genetic evidence implicating natriuretic peptide receptor-3 in cardiovascular disease risk: a Mendelian randomization study.

BMC medicine - 26 Apr 2023

Cronjé Héléne T, Karhunen Ville, Hovingh G Kees, Coppieters Ken, Lagerstedt Jens O, Nyberg Michael, Gill Dipender

Abstract excerpt

BACKGROUND: C-type natriuretic peptide (CNP) is a known target for promoting growth and has been implicated as a therapeutic opportunity for the prevention and treatment of cardiovascular disease (CVD). This study aimed to explore the effect of CNP on CVD risk using the Mendelian randomization (MR) framework. METHODS: Instrumental variables mimicking the effects of pharmacological intervention on CNP were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptors, Atrial Natriuretic Factor

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Identifiers

PMID: 37101178
DOI: 10.1186/s12916-023-02867-x
PMCID: PMC10134514

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