Article
RYR3 gene polymorphisms and cardiovascular disease outcomes in the context of antihypertensive treatment.
The pharmacogenomics journal - 1 Aug 2013
Lynch A I, Irvin M R, Boerwinkle E, Davis B R, Vaughan L K, Ford C E, Aissani B, Eckfeldt J H, Arnett D K, Shrestha S
Abstract excerpt
Nearly one-third of adults in the United States have hypertension, which is associated with increased cardiovascular disease (CVD) morbidity and mortality. The goal of antihypertensive pharmacogenetic research is to enhance understanding of drug response based on the interaction of individual genetic architecture and antihypertensive therapy to improve blood pressure control and ultimately prevent CVD outcomes....
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