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Article

Mendelian randomization: Its impact on cardiovascular disease.

Journal of cardiology - 1 Oct 2018

Kawashiri Masa-Aki, Tada Hayato, Nomura Akihiro, Yamagishi Masakazu

Abstract excerpt

Cardiovascular diseases and their risk factors are inheritable. Single nucleotide polymorphisms in the human genome are found in around 1 in 1000 base pairs, and this may affect the genetic variety of individuals. During meiosis, any genetic information is randomized and is independent of other characteristics. In a Mendelian randomization study (MRS), a genetic variant associated with biomarker is used as a...

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Identifiers

PMID: 29801689
DOI: 10.1016/j.jjcc.2018.04.007

Genes

CAD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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