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Article

twas_sim, a Python-based tool for simulation and power analysis of transcriptome-wide association analysis.

Bioinformatics (Oxford, England) - 4 May 2023

Wang Xinran, Lu Zeyun, Bhattacharya Arjun, Pasaniuc Bogdan, Mancuso Nicholas

Abstract excerpt

SUMMARY: Genome-wide association studies (GWASs) have identified numerous genetic variants associated with complex disease risk; however, most of these associations are non-coding, complicating identifying their proximal target gene. Transcriptome-wide association studies (TWASs) have been proposed to mitigate this gap by integrating expression quantitative trait loci (eQTL) data with GWAS data. Numerous...

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Identifiers

PMID: 37099718
DOI: 10.1093/bioinformatics/btad288
PMCID: PMC10172036

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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