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Article

PascalX: a Python library for GWAS gene and pathway enrichment tests.

Bioinformatics (Oxford, England) - 4 May 2023

Krefl Daniel, Brandulas Cammarata Alessandro, Bergmann Sven

Abstract excerpt

SUMMARY: 'PascalX' is a Python library providing fast and accurate tools for mapping SNP-wise GWAS summary statistics. Specifically, it allows for scoring genes and annotated gene sets for enrichment signals based on data from, both, single GWAS and pairs of GWAS. The gene scores take into account the correlation pattern between SNPs. They are based on the cumulative density function of a linear combination of χ2...

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Identifiers

PMID: 37137228
DOI: 10.1093/bioinformatics/btad296
PMCID: PMC10185402

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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