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African swine fever virus pA104R protein acts as a suppressor of type I interferon signaling

6 Apr 2023

Abstract excerpt

This study evaluates the role of the late viral protein, pA104R, in African swine fever virus immunosuppression. ASFV-encoded pA104R is a putative histone-like protein that is highly conserved throughout different virulent and non-virulent isolates. Previous studies have demonstrated that pA104R plays a vital role in the ASFV replication cycle and is a potential target for antiviral therapy. Here, we demonstrated...

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PMID: 37089552
DOI: 10.3389/fmicb.2023.1169699

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