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African swine fever virus I73R is a critical virulence-related gene: A potential target for attenuation

6 Apr 2023

Abstract excerpt

African swine fever virus (ASFV) is a large, double-stranded DNA virus that causes a fatal disease in pigs, posing a threat to the global pig industry. Whereas some ASFV proteins have been found to play important roles in ASFV–host interaction, the functional roles of many proteins are still largely unknown. In this study, we identified I73R , an early viral gene in the replication cycle of ASFV, as a key...

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PMID: 37023125
DOI: 10.1073/pnas.2210808120

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