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Article

Discovery of decreased ferroptosis in male colorectal cancer patients with KRAS mutations

14 Apr 2023

Abstract excerpt

Aberrant tumor metabolism is a hallmark of cancer in which metabolic rewiring can support tumor growth under nutrient deficient conditions. KRAS mutations occur in 35–45% of all colorectal cancer (CRC) cases and are difficult to treat. The relationship between mutant KRAS and aberrant metabolism in CRCs has not been fully explored and could be a target for intervention. We previously acquired non-targeted...

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PMID: 37086630
DOI: 10.1016/j.redox.2023.102699

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