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Article

Gut Microbiome Mediates Ferroptosis Resistance for Colorectal Cancer Development

26 Jan 2024

Abstract excerpt

Colorectal cancer is a prevalent cancer type in the United States, affecting both genders and influenced by genetics and environmental factors. The role of the gut microbiome in colorectal cancer development and therapy response is a burgeoning field of study. A recent study uncovered that trans-3-indoleacrylic acid (IDA), a microbial metabolite from P. anaerobius, promotes colorectal cancer by inhibiting...

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PMID: 38276975
DOI: 10.1158/0008-5472.can-24-0275

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