Article
Locked nucleic acid real-time polymerase chain reaction method identifying two polymorphisms of hepatitis B virus genotype C2 infections, rt269L and rt269I.
World journal of gastroenterology - 21 Mar 2023
Kim Kijeong, Choi Yu-Min, Kim Dong Hyun, Jang Junghwa, Choe Won Hyeok, Kim Bum-Joon
Abstract excerpt
BACKGROUND: The presence of two distinct hepatitis B virus (HBV) Pol RT polymorphisms, rt269L and rt269I, could contribute to the unique clinical or virological phenotype of HBV genotype C2. Therefore, a simple and sensitive method capable of identifying both types in chronic hepatitis B (CHB) patients infected with genotype C2 should be developed. AIM: To develop a novel simple and sensitive locked nucleic acid...
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