Article
Novel approach for quantification of hepatitis C virus in liver cirrhosis using real-time reverse transcriptase PCR.
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract - 1 Jan 2012
Maudar Kewal Krishan, Gandhi Puneet, Mishra Pradyumna Kumar, Varshney Subodh, Punde Ramprakash, Bhargav Arpit
Abstract excerpt
BACKGROUND: Hepatitis C virus (HCV) infects nearly 3% of the population worldwide and is a major cause of acute and chronic infections leading to fibrosis, cirrhosis, and hepatocellular carcinoma. Current laboratory diagnosis of HCV is based on specific antibody detection (anti-hepatitis C virus (anti-HCV)) in serum. As HCV replicates in the liver cells, detection and localization of HCV RNA in liver tissue are...
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