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Simultaneous genotyping and quantification of hepatitis B virus for genotypes B and C by real-time PCR assay.

Journal of clinical microbiology - 1 Oct 2010

Zhao Yao, Zhang Xiu-Yu, Guo Jin-Jun, Zeng Ai-Zhong, Hu Jie-Li, Huang Wen-Xiang, Shan You-Lan, Huang Ai-Long

Abstract excerpt

Hepatitis B virus (HBV) is an important cause of human chronic liver diseases and is a major public health problem. Viral load and HBV genotype play critical roles in determining clinical outcomes and response to antiviral treatment in hepatitis B patients. Viral genotype detection and quantification assays are currently in use with different levels of effectiveness. In this study, the performance of a real-time...

Topics

DNA Primers
DNA, Viral
Genotype
Hepatitis B virus
Hepatitis B, Chronic
Humans
Molecular Sequence Data
Oligonucleotide Probes
Polymerase Chain Reaction
Sensitivity and Specificity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Sequence Analysis, DNA

Viral Load

Source

Open in PubMed Open full text

Identifiers

PMID: 20720032
DOI: 10.1128/JCM.00741-10
PMCID: PMC2953110

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